K48 polyubiquitination
1 paper1 finding
- Animals1
Interventions
1Contextual fear conditioning
upin rats1
1 study
Contextual fear conditioning
upin rats1
Contextual fear conditioning increases K48 polyubiquitination in rats.
“contextual fear conditioning led to an increase in proteasome activity and K48 polyubiquitin protein targeting in the hippocampus of aged male rats”
Animalsagedhippocampusmales
Dysregulation of baseline and learning-dependent protein degradation in the aged hippocampus
Brain research bulletin13 Jun 2024
Latest
Learning & Memory
Differential impacts of advanced age and sex in age-related trace fear memory impairment in rats
Experiments in ratsMechanisms
Brain Research Bulletin
Dysregulation of baseline and learning-dependent protein degradation in the aged hippocampus
Experiments in ratsMechanisms
Clinical and Translational Medicine
Inflammasome activation and metabolic remodelling in p16-positive aging cells aggravates high-fat diet-induced lung fibrosis by inhibiting NEDD4L-mediated K48-polyubiquitin-dependent degradation of SGK1
Experiments in animalsMechanisms
Journal of Cachexia, Sarcopenia and Muscle
Loss of FoxOs in muscle increases strength and mitochondrial function during aging
Experiments in miceOxidative phosphorylation