Joint space width

1. CTX-II is associated with joint space width in humans (R = 0.43, p < 0.05).

   “The 12 months change in CTX-II in OA patients with elevated CTX-II at baseline correlated with the change in average joint space width observed after 36 months (R = 0.43, p < 0.05).”

   Human trialknee OA with elevated baseline CTX-II36 months

   Osteoarthritic patients with high cartilage turnover show increased responsiveness to the cartilage protecting effects of glucosamine sulphate

   Clinical and experimental rheumatology·Jan 1, 2004

More on CTX-II

1. Joint space width is associated with joint space narrowing in humans (r=-0.34, P=0.003).

   “In the placebo group, baseline JSW was significantly and negatively correlated with the joint space narrowing observed after 3 years (r=-0.34, P=0.003).”

   Human trialin placebo groupknee3 years

   Correlation between radiographic severity of knee osteoarthritis and future disease progression. Results from a 3-year prospective, placebo-controlled study evaluating the effect of glucosamine sulfate

   Osteoarthritis and cartilage·Jan 1, 2003

More on Joint space narrowing