Intracellular branched-chain amino acid abundance

1. Replicative ageing decreases intracellular branched-chain amino acid abundance in mouse cells.

   “Branched chain amino acids L-leucine, L-isoleucine and L-valine, and L-carnitine were less abundant in aged versus control myotubes.”

   CellsP48–51 versus P7–11C2C12 myotubes

   Replicative ageing perturbs the metabolic signature of murine C 2 C 12 skeletal myotubes

   bioRxiv (Cold Spring Harbor Laboratory)·Apr 21, 2022Preprint

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