INTERLEUKIN-12

4 papers1 finding

Humans1
Animals2

Associations

1

Low hand grip strength

upin humans1OR 1.03

1 study

INTERLEUKIN-12 raises the risk of low hand grip strength in humans (OR 1.03, 95% CI 1.00-1.07).
“IL-12, and vascular endothelial growth factor (VEGF) was associated with the higher risk of low hand grip strength according to the IVW method [R = 1.05, 95% CI = 1.01-1.10, P = 0.028”
HumansIVW Mendelian randomization
The causal association between circulating cytokines with the risk of frailty and sarcopenia under the perspective of geroscience
Frontiers in endocrinology5 Mar 2024

Latest

3 in 12 months

The Journal of Investigative Dermatology9 Sep

Aging-related IgG accumulation promotes skin inflammation

Experiments in miceInflammation

Arthritis & Rheumatology24 Aug

Interleukin-12 Signaling Promotes Podocyte Senescence in Lupus Nephritis

Experiments in miceJAK–STAT signalling

Aging and Disease1 Jan

Sex- and Age-Dependent Metabolic and Inflammatory Pathways in Cardiomyopathy: The Role of Sirtuins, Inflammaging and Mitochondrial Homeostasis

ReviewSirtuin signalling

Frontiers in Endocrinology20 Mar

The causal association between circulating cytokines with the risk of frailty and sarcopenia under the perspective of geroscience

Mendelian randomisation in 8,293 peopleMuscle

Journal of Virology1 Feb

SHIV-C109p5 NHP induces rapid disease progression in elderly macaques with extensive GI viral replication

Experiments in 5 monkeysMechanisms

The Journal of Nutrition1 Oct

Life span is prolonged in food-restricted autoimmune-prone (NZB x NZW)F(1) mice fed a diet enriched with (n-3) fatty acids

Experiments in miceDietary restriction

The Journal of Infectious Diseases18 Jul

The senescence-accelerated mouse shows aging-related defects in cellular but not humoral immunity against influenza virus infection

Experiments in miceBlood and immune system