Insr mRNA

1. Caloric restriction increases Insr mRNA in mice (15% to 25% higher than ad libitum feeding).

   “increased insulin receptor mRNA by 15% to 25% over the levels in animals fed ad libitum.”

   AnimalsC3B10RF1 mice; compared with ad libitum feedingliver52% reduction in dietary caloriesfemales

   Aging and restriction of dietary calories increases insulin receptor mRNA, and aging increases glucocorticoid receptor mRNA in the liver of female C3B10RF1 mice

   Journal of gerontology·1 Nov 1991

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