Insoluble amyloid-beta
3 papers study it1 finding
- Animals3
Interventions
1PF-04691502
downin mice1
1 study
PF-04691502
downin mice1
PF-04691502 decreases insoluble amyloid-beta in mice.
“significantly reduced insoluble Aβ accumulation in the brain”
Animalsin APP/PS1 miceoral administrationbrain1 mg/kg12 weeks
PF-04691502, a PI3K/mTOR Dual Inhibitor, Ameliorates AD-like Pathology in a Mouse Model of AD
Cells
Latest
1 paper in 12 monthsAAIC 2025 Abstract
Tau pathology in triple knock‐in mouse model of Alzheimer's Disease expressing APOE3 and APOE4
Experiments in miceAPOE
Neurobiology of Aging
The TgF344-AD rat: behavioral and proteomic changes associated with aging and protein expression in a transgenic rat model of Alzheimer's disease
Experiments in ratsMechanisms