Papers on IL-1β and IL-6

114 papers4 new in 30 days

Wednesday, March 29

Molecular Nutrition & Food ResearchMar 29

Dietary Intervention with the Gut Microbial Metabolite Urolithin A Attenuates Lipopolysaccharide-Induced Neuroinflammation and Cognitive Deficits via the Sirt1/acetyl-NF-κB Signaling Pathway

Experiments in miceUrolithin A

Paper

Thursday, December 15

Cell ProliferationDec 15

ZNF281 drives hepatocyte senescence in alcoholic liver disease by reducing HK2-stabilized PINK1/Parkin-mediated mitophagy

Experiments in miceMitophagy

Paper

Tuesday, December 13

American Journal of Translational ResearchDec 13

Effect of dexmedetomidine-assisted ultrasound-guided lower extremity nerve block on postoperative cognitive function in elderly patients undergoing hip surgery

Cohort study of 60 peopleInterventions

Paper

Sunday, November 27

International Journal of Molecular SciencesNov 27

Organophosphorus Flame Retardant TCPP Induces Cellular Senescence in Normal Human Skin Keratinocytes: Implication for Skin Aging

Experiments in human cellsCellular senescence

Paper

Saturday, November 5

The Journal of Surgical ResearchNov 5

Nicotinamide Mononucleotide Attenuates LPS-Induced Acute Lung Injury With Anti-Inflammatory, Anti-Oxidative and Anti-Apoptotic Effects

Experiments in miceNicotinamide mononucleotide

Paper

Wednesday, October 12

Molecular and Cellular BiochemistryOct 12

Swimming exercise activates peroxisome proliferator-activated receptor-alpha and mitigates age-related renal fibrosis in rats

Experiments in ratsRenal fibrosis

Paper

Wednesday, October 5

Research SquareOct 5

Adiponectin attenuates splenectomy-induced cognitive deficits by alleviating neuroinflammation and oxidative stress via the TLR4/MyD88/NF-κb signaling pathway in aged rats

Preprint: experiments in ratsInterventions

Paper

Tuesday, September 27

Biochemistry BiokhimiiaSep 27

Anti-Inflammatory Properties of Metformin During Cultivation of Primary Rat Astrocytes in a Medium with High Glucose Concentration

Experiments in rat cellsMetformin

Paper

Tuesday, September 20

Frontiers in ImmunologySep 20

Extracellular vesicle-associated microRNA-30b-5p activates macrophages through the SIRT1/ NF-κB pathway in cell senescence

Experiments in miceSirtuin signaling

Paper

Sunday, July 17

Molecular Biology ReportsJul 17

Combination of nicotinamide mononucleotide and troxerutin induces full protection against doxorubicin-induced cardiotoxicity by modulating mitochondrial biogenesis and inflammatory response

Experiments in 30 ratsNicotinamide mononucleotide

Paper

Monday, June 20

International Journal of Oral ScienceJun 20

Interleukin-13 promotes cellular senescence through inducing mitochondrial dysfunction in IgG4-related sialadenitis

Study in peopleCellular senescence

Paper

Wednesday, May 18

Biomaterials ScienceMay 18

p16INK4a-siRNA nanoparticles attenuate cartilage degeneration in osteoarthritis by inhibiting inflammation in fibroblast-like synoviocytes

Experiments in miceOsteoarthritis

Paper

Thursday, May 5

European Journal of NutritionMay 5

The influence of association between aging and reduced protein intake on some immunomodulatory aspects of bone marrow mesenchymal stem cells: an experimental study

Experiments in miceBones and joints

Paper

Tuesday, April 26

bioRxivApr 26

Salivary Proinflammatory Cytokines IL-1β, IL-6 and TNF Decrease With Age

Preprint: cross-sectional study of 64 peopleTNF signaling

Paper

Saturday, March 26

AntioxidantsMar 26

Vitamin K2 (Menaquinone-7) Reverses Age-Related Structural and Cognitive Deterioration in Naturally Aging Rats

Experiments in ratsInterventions

Paper

Monday, March 21

Journal of Molecular NeuroscienceMar 21

TREM2 and CD163 Ameliorate Microglia-Mediated Inflammatory Environment in the Aging Brain

Experiments in miceInflammation

Paper

Saturday, January 29

The European Respiratory JournalJan 29

Pulmonary infection by SARS-CoV-2 induces senescence accompanied by an inflammatory phenotype in severe COVID-19: possible implications for viral mutagenesis

Case-control study of 43 peopleSenescence-associated secretory phenotype (SASP)

Paper

Monday, November 15

Journal of NeuroinflammationNov 15

Metabolic reprogramming mediates hippocampal microglial M1 polarization in response to surgical trauma causing perioperative neurocognitive disorders

Experiments in micePerioperative neurocognitive disorder

Paper

Sunday, May 9

Nan Fang Yi Ke Da Xue Xue BaoMay 9

Effects of dexmedetomidine doses on postoperative cognitive dysfunction and serum β- amyloid and cytokine levels in elderly patients after spine surgery: a randomized controlled trial

Randomized trial in 120 peoplePostoperative cognitive dysfunction

Paper

Thursday, May 6

Journal of NeurophysiologyMay 6

Exogenous insulin-like growth factor 1 attenuates sevoflurane anesthesia-induced cognitive dysfunction in aged rats

Experiments in ratsPostoperative cognitive dysfunction

Paper

Friday, March 12

BiogerontologyMar 12

Anti-SASP and anti-inflammatory activity of resveratrol, curcumin and β-caryophyllene association on human endothelial and monocytic cells

Experiments in human cellsCurcumin

Paper

Saturday, February 6

Frontiers in PharmacologyFeb 6

Detrimental Effects of Chronic L-Arginine Rich Food on Aging Kidney

Experiments in miceKidney

Paper

Friday, January 1

Indian Journal of PharmacologyJan 1

Correlation between serum pro inflammatory cytokines and clinical scores of knee osteoarthritic patients using resveratrol as a supplementary therapy with meloxicam

Randomized trial in 110 peopleResveratrol

Paper

Wednesday, December 30

Experimental GerontologyDec 30

Reduced levels of plasma selenium are associated with increased inflammation and cardiovascular disease in an Italian elderly population

Case-control study of 858 peopleCardiovascular disease

Paper

Thursday, November 26

AgingNov 26

Pharmacological blockade of TNFα prevents sarcopenia and prolongs survival in aging mice

Experiments in miceSarcopenia

Paper

Thursday, November 19

Neural PlasticityNov 19

Electroacupuncture Improves Cognitive Function in Senescence-Accelerated P8 (SAMP8) Mice via the NLRP3/Caspase-1 Pathway

Experiments in 30 miceInterventions

Paper

Monday, November 16

Experimental GerontologyNov 16

2,4-Dihydroxyphenyl-benzo[d]thiazole (MHY553), a synthetic PPARα agonist, decreases age-associated inflammatory responses through PPARα activation and RS scavenging in the skin

Experiments in ratsSkin

Paper

Tuesday, November 10

Brain, Behavior, and ImmunityNov 10

Assessment of neuroinflammation in the aging hippocampus using large-molecule microdialysis: Sex differences and role of purinergic receptors

Experiments in ratsInflammation

Paper

Monday, July 6

BoneJul 6

Inhibition of cellular communication network factor 1 (CCN1)-driven senescence slows down cartilage inflammaging and osteoarthritis

Experiments in miceOsteoarthritis

Paper

Wednesday, June 24

PLOS OneJun 24

Increased systemic inflammation and altered distribution of T-cell subsets in postmenopausal women

Cross-sectional study of 69 peopleInflammation

Paper