Hub genes

1 paper1 finding

In silico1

Associations

1

VCAN

upin silico1

1 study

VCAN is associated with hub genes in silico.
“Four hub genes-PPARG, IRF7, VCAN, and SDC1-were identified as central regulators.”
In silico
Mechanisms and targets of vascular natural aging from a systems biology perspective
Current problems in cardiology28 Nov 2025

Latest

42 in 12 months

bioRxiv29 Sep

T cell KRAS upregulation is linked to premature coronary disease

Profiling blood and plaque samples from 12 patients and 21 controls linked elevated KRAS in senescent CD8+ T cells to premature coronary artery disease.Profiling blood and plaque samples from 12 patients and 21 controls linked elevated KRAS in senescent CD8+ T cells to premature coronary artery disease.

Preprint: case-control study in peopleKRAS

BMC Pharmacology & Toxicology26 Sep

Assessing the toxicological effects of synthetic musk ketone using the Caenorhabditis elegans model

Experiments in wormsMechanisms

Aging Cell23 Sep

Transplantation of Elderly Human Gut Microbiota Into Pigs Reprograms Intestinal Barrier Function, Plasma Metabolome, and Gut Mucosal Transcriptomic Landscape

Experiments in pigsFecal microbiota transplantation

FASEB Journal23 Sep

Integrative Multi-Omics and Machine Learning Reveal Senescent Fibroblast-Associated ADAMTS2 as a Critical Indicator of Intestinal Inflammation in IBD

Experiments in human cellsCellular senescence

Research Square22 Sep

Identification of Cellular Senescence-Related Hub Genes and Their Association with Immune Infiltration in Abdominal Aortic Aneurysm: A Comprehensive Bioinformatics Analysis

Preprint: computational studyAbdominal aortic aneurysm

bioRxiv14 Sep

Comparative transcriptomic analysis reveals conserved injury responses and divergent molecular responses underlying early regenerative competence following traumatic brain injury

Preprint: computational studyImmune response

bioRxiv10 Sep

A Single-cell Spatiotemporal Atlas Encoding Age-dependent Evolution of the Ischemic Penumbra

Preprint: experiments in miceSingle-cell omics

Environment International6 Sep

Cross-sectional and longitudinal relationships between exposure to polychlorinated biphenyls and predicted 10-year atherosclerotic cardiovascular disease risk: Integrated epidemiological and bioinformatics analysis

Cohort study in peopleAtherosclerotic cardiovascular disease

International Journal of Medical Sciences4 Sep

TNFSF13 Drives Atherosclerosis Progression by Targeting Macrophage Senescence

Cohort study in peopleCellular senescence

Biomedicines27 Aug

Identification of Progressive Islet Biomarkers for Type 2 Diabetes by Integrated Transcriptomics and Mendelian Randomization: Alterations Spanning the Normal Glucose Tolerance-Impaired Glucose Tolerance-Type 2 Diabetes Continuum

Cohort study of 181 peopleImpaired glucose tolerance