Heat shock protein and antioxidant gene induction

1. Reserpine decreases heat shock protein and antioxidant gene induction in flies.

   “under heat stress, reserpine blunts the induction of canonical protective genes, including heat shock proteins and antioxidant genes”

   Model organismsheat stress

   Reserpine prolongs lifespan but compromises heat-stress resilience in Drosophila melanogaster

   bioRxiv (Cold Spring Harbor Laboratory)·24 Aug 2025Preprint

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