Fumarate

Biomarker

1 paper3 findings

  • Animals1

Interventions

1

Tributyl phosphate

upin rats1

1 study
  1. Tributyl phosphate increases fumarate in rats.

    Animalstributyl phosphate exposure

    Tributyl phosphate caused signs of liver aging in rats

    Ecotoxicology and environmental safety9 Oct 2026

More on Tributyl phosphate

Effects

2

FPR2

upin rats1

1 study
  1. Fumarate activates FPR2 in rats.

    Animalstributyl phosphate exposure; fumarate-mediated mitochondrial DNA escapeliver

    Tributyl phosphate caused signs of liver aging in rats

    Ecotoxicology and environmental safety9 Oct 2026

More on FPR2

Mitochondrial DNA escape

upin rats1

1 study
  1. Fumarate induces mitochondrial DNA escape in rats.

    Animalstributyl phosphate exposureliver

    Tributyl phosphate caused signs of liver aging in rats

    Ecotoxicology and environmental safety9 Oct 2026

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Ecotoxicology and Environmental Safety

Tributyl phosphate caused signs of liver aging in rats

An experiment in rats linked the chemical’s effects to fumarate, a substance involved in metabolism, and DNA escaping from cells’ energy-producing structures.An experiment in rats linked the chemical’s effects to fumarate, a substance involved in metabolism, and DNA escaping from cells’ energy-producing structures.

Experiments in ratsMechanisms