FMO-2 upregulation

genes required for clk-1 longevity is required for FMO-2 upregulation in worms.

“We found that in all cases, genes required for clk-1 longevity are also required for the upregulation of fmo-2 in clk-1 worms.”

Model organismsclk-1 mutants

Mild mitochondrial impairment activates overlapping longevity pathways converging on the flavin-containing monooxygenase FMO-2

Frontiers in aging·25 Mar 2026