FMO-2 expression
1 paper1 finding
- Model organisms1
Upstream
1Clk-1, ISP-1 and NUO-6 mutations
upin worms1
1 study
Clk-1, ISP-1 and NUO-6 mutations
upin worms1
clk-1, isp-1 and nuo-6 mutations increase FMO-2 expression in worms.
“We found that fmo-2, but not other fmo genes, are specifically upregulated in the long-lived mitochondrial mutants clk-1, isp-1 and nuo-6.”
Model organismsclk-1, isp-1 and nuo-6 mitochondrial mutants
Frontiers in aging25 Mar 2026
Latest
3 in 12 monthsFrontiers in Aging
Mild mitochondrial impairment activates overlapping longevity pathways converging on the flavin-containing monooxygenase FMO-2
Experiments in wormsMitochondrion
Cell Communication and Signaling
Bacterial exopolysaccharides mediate activation of flavin-containing monooxygenase 2 to extend lifespan in Caenorhabditis elegans
Experiments in wormsInterventions
bioRxiv
The 1 –Cys peroxiredoxin, PRDX-6, suppresses a pro-survival response, including the Flavin monoxygenase, FMO-2, that protects against fungal and bacterial infection
Preprint: experiments in model organismsMechanisms
MicroPublication Biology
Perception of Enterococcus faecalis without infection induces fmo-2 in C. elegans
Experiments in model organismsMechanisms