Expression of pathways involved in synapse formation

1. 17-alpha-estradiol increases expression of pathways involved in synapse formation in rats.

   “decreased expression levels of pathways involved in synapse formation in neurons initiated by aging were significantly attenuated by 17α-estradiol.”

   Animalshypothalamic neuronslong-term administrationmales

   The effects of 17α-estradiol treatment on endocrine system revealed by single-nucleus transcriptomic sequencing of hypothalamus

   eLife·10 Sep 2025Preprint

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