Disease status increases epigenetic ageing in cattle.
“Our results revealed accelerated epigenetic ageing in cows susceptible to diseases, suggesting a link between health-related stress and disrupted DNA methylation dynamics.”
Longer telomeres were linked to lower odds of interstitial lung disease, with an odds ratio of 0.59 per standard-deviation increase in length.Longer telomeres were linked to lower odds of interstitial lung disease, with an odds ratio of 0.59 per standard-deviation increase in length.
In an observational study of 1,861 adults, employment patterns from ages 18 to 50 were largely unrelated to DNA-based measures of accelerated aging.In an observational study of 1,861 adults, employment patterns from ages 18 to 50 were largely unrelated to DNA-based measures of accelerated aging.
Cross-sectional study of 1,861 adults aged 55 and olderPopulations
Limit: Retrospective employment histories may misclassify short-term, informal or intermittent jobs through recall error
An observational analysis of 126 whole-blood DNA profiles identified 409 genes with age-linked changes in chemical marks throughout life.An observational analysis of 126 whole-blood DNA profiles identified 409 genes with age-linked changes in chemical marks throughout life.
An epigenetic clock built from 894 domestic dogs predicted mortality and linked faster biological aging to larger body size and male sex.An epigenetic clock built from 894 domestic dogs predicted mortality and linked faster biological aging to larger body size and male sex.