ECM stiffness

1. Senolytics increase ECM stiffness in silico (Recovery from 0.74 toward baseline; units not stated).

   “mean ECM stiffness recovering from 0.74back toward baseline while an untreated control saturates at complete degeneration.”

   In silicoSpatial simulation compared with untreated control; illustrative parameters

   Reversing Cellular Senescence and Extracellular Matrix Degeneration: A Multiscale Model of Senolytic Intervention and Verifiable Recovery Predictions

   Zenodo (CERN European Organization for Nuclear Research)·1 Aug 2026Preprint

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