Dopaminergic neuron survival

1 paper studies it7 more mention it

Model organisms1

Funding

1 grant since 2018

National Institute of Neurological Disorders and StrokeUS$2.6m

LRRK in Autophagy Function and Dopaminergic Neuron Survival
National Institute of Neurological Disorders and StrokeBrigham and Women's HospitalUS$670.5k2010–2023

Latest

3 papers in 12 months

Science BulletinJul 17

Biallelic hexose-6-phosphate dehydrogenase variants cause mitochondrial dysfunction underlying Parkinson's disease

Genetic association study in peopleMitochondrion

bioRxivMay 5

“Plasma Membrane Calcium ATPase Downregulation in Dopaminergic Neurons Induces Presynaptic Dysfunction and Neuronal Vulnerability In Vivo and In Vitro”

Preprint: experiments in fliesMechanisms

NeuroprotectionFeb 25

Exercise, exerkines, and muscle-brain crosstalk in Parkinson's disease

ReviewInterventions

Journal of Parkinson's DiseaseJun 16

Reduced expression of Pss gene in Drosophila cortex glia causes dopaminergic cell death

Experiments in fliesMechanisms

bioRxivApr 9

HSF1 Activator Azadiradione Ameliorates Parkinson’s Disease and Extends Lifespan in Preclinical Models: Analysis of Underlying Molecular Mechanism

Preprint: experiments in miceParkinson's disease

Experimental Brain ResearchMar 2

Autophagy and UPS pathway contribute to nicotine-induced protection effect in Parkinson's disease

Experiments in wormsNicotine

Nature AgingNov 14

Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology

Experiments in human cellsSenolytics

Frontiers in NeuroscienceAug 10

C. elegans MANF Homolog Is Necessary for the Protection of Dopaminergic Neurons and ER Unfolded Protein Response

Experiments in model organismsMechanisms