Differential promoter methylation

1. Bezisterim induces differential promoter methylation in humans (2581 genes with significant differential promoter methylation).

   “Genome-wide methylation profiling revealed 2581 genes with significant differential promoter methylation (DPM) between the bezisterim and placebo groups.”

   Human trialmild-to-moderate Alzheimer's disease; versus placebo30 weeks

   Bezisterim-associated anti-inflammatory epigenetic modulation of age acceleration and Alzheimer’s disease genes

   medRxiv·22 Oct 2025Preprint

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