Papers on delirium

In a preprint trial, delirium occurred in 21.2% of older patients given the sedative versus 45.7% given placebo within seven days of hip fracture surgery.In a preprint trial, delirium occurred in 21.2% of older patients given the sedative versus 45.7% given placebo within seven days of hip fracture surgery.

Preprint: randomized trial · 490 peoplePostoperative delirium

Paper

Tuesday, October 20

European Journal of AnaesthesiologyOct 20

Delirium after surgery linked to poorer function a year later

At one year, patients with delirium had disability scores 4.6 points higher than those without delirium, after researchers accounted for other factors.At one year, patients with delirium had disability scores 4.6 points higher than those without delirium, after researchers accounted for other factors.

Upright adults in dark blue-green cluster outside a care building, while lighter blue figures stand farther apart around them.

Cohort · 1,899 peoplePostoperative delirium

Paper

MaturitasOct 20

Mortality amongst older patients with delirium superimposed on dementia and malnutrition: A six-year follow-up study

Cohort study of 554 peopleDelirium

Paper

Monday, October 19

Chinese Journal of Multiple Organ Diseases in the ElderlyOct 19

Correlation of preoperative ultrasound quantitative parameters of the quadriceps femoris with new-onset frailty after hip replacement in elderly patients with femoral neck fracture

Cohort study of 180 peopleFemoral neck fracture

Paper

Sunday, October 18

Scientific ReportsOct 18

Development and internal validation of a clinical risk score for early delirium detection in older emergency department patients

Cohort study of 380 peopleDelirium

Paper

Frontiers in Aging NeuroscienceOct 18

Circulating and cerebrospinal fluid soluble TREM2 levels and risk of perioperative neurocognitive disorders in surgical patients: a systematic review and meta-analysis

PRISMA 2020 flow diagram of study selection.

Meta-analysis of observational studiesBiomarkers

Paper

Thursday, October 15

DeliriumOct 15

Examining the Link Between Inflammation and Post-Operative Delirium in a Hip Fracture Repair Cohort of Older Adults

Box plots of biomarker (TNFR1 plasma & CSF) by Delirium status.

Cohort study in peoplePostoperative delirium

Paper

Wednesday, October 14

Spine Surgery and Related ResearchOct 14

Functional Recovery and Home Discharge after Spine Surgery in Nonagenarians: The Role of Cognitive Status and Acute Exacerbation of Cervical Myelopathy

Cohort study of 27 peoplePopulations

Paper

Tuesday, October 13

AnaesthesiaOct 13

Frailty linked to higher death risk after surgery and intensive care

Among 5,398 matched patients aged 90 or older, frailty was linked to higher one-year mortality than no frailty, with a hazard ratio of 1.66.Among 5,398 matched patients aged 90 or older, frailty was linked to higher one-year mortality than no frailty, with a hazard ratio of 1.66.

Cohort · 5,398 peoplePopulations

Paper

Frontiers in MedicineOct 13

Sarcopenia and cognitive impairment after hip fracture in older adults: a narrative review and conceptual rehabilitation framework

Original figure developed by the authors for this manuscript.

Study in peopleHip fracture

Paper

Revista Fisio&terapiaOct 13

Influence of sarcopenia on postoperative outcomes in older adults undergoing surgical treatment for hip fracture: a narrative review

ReviewHip fracture

Paper

Sunday, October 11

CureusOct 11

Nutritional risk linked to early death after hip fracture

Within 28 days, 14.8% of hip-fracture patients with nutritional risk died, compared with 5.2% of those with normal nutritional status.Within 28 days, 14.8% of hip-fracture patients with nutritional risk died, compared with 5.2% of those with normal nutritional status.

Twenty-eight-day mortality rate by nutrition risk status (any risk vs. normal)

Cohort study of 691 peopleHip fracture

Paper

Saturday, October 10

Chinese General PracticeOct 10

Evaluation and Comparison of Multidimensional Functional Disability in Geriatric Comorbidities and Comorbid Acute Kidney Injury

Cross-sectional study of 114 peopleAcute kidney injury

Paper

The American Journal of Geriatric PsychiatryOct 10

Domain-Specific Subjective Cognitive complaints and Cognitive Test Performance After Surgery in Older Adults: A Patient-Centered Prospective Cohort Study

Cohort study of 197 peopleBiomarkers

Paper

Friday, October 9

Frontiers in AgingOct 9

Association of preoperative frailty and postoperative delirium with one-year mortality after surgery in older patients with hip fractures

Cohort study of 1,715 peoplePostoperative delirium

Paper

Thursday, October 8

Alzheimer's & DementiaOct 8

Comorbidities and health-care use prior to early-onset Alzheimer's disease: A population-based case-control study

Odds ratios for comorbidities among EOAD patients compared to matched controls across three pre‐diagnostic time intervals (1–5, 6–10, and 11–15 years before EOAD diagnosis).

Case-control study of 4,035 peoplePopulations

Paper

BMC GeriatricsOct 8

Application of artificial intelligence to electronic health record data in long-term care facilities: a scoping review

Systematic reviewBiomarkers

Paper

Monday, October 5

GerontologyOct 5

Geriatric co-management linked to lower delirium odds

Compared with usual care, co-management was associated with lower odds of hospice or in-hospital death (OR 0.27) and delirium (OR 0.29).Compared with usual care, co-management was associated with lower odds of hospice or in-hospital death (OR 0.27) and delirium (OR 0.29).

Dark blue-green patients surrounded by clinicians have fewer tangles above their heads than gray patients beside a lone clinician.

Cohort study of 4,359 peopleDelirium

Paper

European Geriatric MedicineOct 5

Comparing three approaches to delirium identification in older patients presenting to the emergency department

Cohort study of 655 peopleDelirium

Paper

Research SquareOct 5

Age and PITX2 variant predict atrial fibrillation after heart surgery

In 364 cardiac surgery patients, age (odds ratio 1.71 per decade) and a PITX2 variant (odds ratio 1.91) independently predicted postoperative atrial fibrillation, while…In 364 cardiac surgery patients, age (odds ratio 1.71 per decade) and a PITX2 variant (odds ratio 1.91) independently predicted postoperative atrial fibrillation, while inflammatory markers did not.

Association of four atrial-fibrillation-associated variants with new-onset atrial fibrillation.

Preprint: cohort study of 364 peopleAtrial fibrillation

Paper

Sunday, October 4

European Journal of Clinical InvestigationOct 4

Delirium after head injury is linked to higher dementia risk

In a matched cohort, patients with delirium within 14 days of brain trauma had higher two-year risk of dementia (hazard ratio 2.47).In a matched cohort, patients with delirium within 14 days of brain trauma had higher two-year risk of dementia (hazard ratio 2.47).