CPT1A: aging research evidence

Journal of Proteome ResearchOct 24

Semaglutide and Tirzepatide Suppress Hepatic Fatty Acid Uptake and Fatty Acid β-Oxidation in High-Fat Diet-Induced Obesity Mice

Experiments in miceTirzepatide

Paper

Cancer ResearchNov 1

Fasting-Mimicking Diet Drives Antitumor Immunity against Colorectal Cancer by Reducing IgA-Producing Cells

Experiments in miceColorectal cancer

Paper

ESC Congress 2026 AbstractOct 26

Betulinic acid reduced signs of artery aging in mice

In genetically altered mice fed a high-fat diet, the compound reduced artery stiffness and the thickness of two layers of the carotid artery wall.In genetically altered mice fed a high-fat diet, the compound reduced artery stiffness and the thickness of two layers of the carotid artery wall.

Mouse studyInterventions

Paper

Biochemical PharmacologyOct 24

Experimental peptide reduced diabetic kidney injury in mice

Experiments in diabetic mice linked the peptide’s kidney benefits to the breakdown of stored fat and reduced signs of cells entering a nondividing state.Experiments in diabetic mice linked the peptide’s kidney benefits to the breakdown of stored fat and reduced signs of cells entering a nondividing state.

Mouse studyKidney

Paper

Clinical EpigeneticsOct 21

Blood fat links to DNA marks replicated in Korean adults

Links at five previously identified DNA sites were confirmed in two additional Korean groups of 389 and 417 adults.Links at five previously identified DNA sites were confirmed in two additional Korean groups of 389 and 417 adults.

Cross-sectional · 1,527 peopleBiomarkers

Paper

Research SquareOct 16

Metformin promotes the expansion of CD8+ central memory T cells by offsetting Pentose phosphate pathway

Preprint: experiments in human cellsMetformin

Paper

eLifeOct 8

Periodic red light exposure eases cellular aging in mice

In aged mice, periodic red light exposure raised histone acetylation across tissues and reduced SIRT4 levels in skin cells to activate lipid metabolism.In aged mice, periodic red light exposure raised histone acetylation across tissues and reduced SIRT4 levels in skin cells to activate lipid metabolism.

Experiments in miceInterventions

Paper

Molecular Biology ReportsJul 10