Journal of Cachexia, Sarcopenia and Muscle
Blood proteins linked to later amyotrophic lateral sclerosis
Nine blood proteins were linked to later disease in 52,584 UK Biobank participants followed for an average of 11.8 years.Nine blood proteins were linked to later disease in 52,584 UK Biobank participants followed for an average of 11.8 years.
Cohort · 52,584 peopleAmyotrophic lateral sclerosis
Who was studied52,584 UK Biobank participants without ALS at baseline, mean 11.8 years
What changedHigher blood NEFL levels were linked to higher risk of later ALS (hazard ratio 2.897)
The catchEarly ALS may change blood proteins, rather than protein changes causing later ALS