Higher irregularity measures were linked to greater odds of dementia, with odds ratios ranging from 1.32 to 2.36 in 4,854 people.Higher irregularity measures were linked to greater odds of dementia, with odds ratios ranging from 1.32 to 2.36 in 4,854 people.
Cross-sectional study of 4,854 participants from population-based studiesDementia
Limit: Dementia may precede irregular blood pressure patterns rather than result from them
An observational analysis found that brain-structure measures added information about progression to mild cognitive impairment and dementia beyond a clinical rating of…An observational analysis found that brain-structure measures added information about progression to mild cognitive impairment and dementia beyond a clinical rating of impairment.
Preprint: cohort study of Alzheimer’s Disease Neuroimaging Initiative participantsDementia
Limit: Baseline disease severity may differ despite similar clinical ratings, potentially explaining the added prediction
A measure of prediction performance rose from 0.79 for symptoms alone to 0.90 when blood biomarkers were added.A measure of prediction performance rose from 0.79 for symptoms alone to 0.90 when blood biomarkers were added.
In an observational study of 735 people, other brain vessel injuries strengthened links between shorter sleep and brain lesions in some diagnostic groups.In an observational study of 735 people, other brain vessel injuries strengthened links between shorter sleep and brain lesions in some diagnostic groups.