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Brainstem white matter ratio

There is 1 paper on brainstem white matter ratio in aging research: 1 observational study in people.

Biomarker

1 paper studies it3 findings

See all 1 papers on brainstem white matter ratio

“Clinical severity was negatively associated with the WM ratio.”
Loss of brainstem white matter predicts onset and motor neuron symptoms in C9orf72 expansion carriers: a GENFI studyJournal of neurology2022doi:10.1007/s00415-022-11435-x
  • Humans1

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1

C9ORF72EXPANSION

no changein humans1downin humans1

1 study

  1. C9ORF72EXPANSION was not clearly linked with brainstem white matter ratio in humans (presymptomatic carriers compared with non-carriers).

    “No differences were found between presymptomatic carriers and non-carriers.”

    Humanspresymptomatic carriers compared with non-carriersbrainstem

    Loss of brainstem white matter predicts onset and motor neuron symptoms in C9orf72 expansion carriers: a GENFI study

    Journal of neurology

  2. C9ORF72EXPANSION is linked with lower brainstem white matter ratio in humans (symptomatic carriers compared with non-carriers and presymptomatic carriers).

    “A reduced WM ratio was found in all brainstem subregions in symptomatic carriers compared to both noncarriers and pre-symptomatic carriers.”

    Humanssymptomatic carriers compared with non-carriers and presymptomatic carriersbrainstem

    Loss of brainstem white matter predicts onset and motor neuron symptoms in C9orf72 expansion carriers: a GENFI study

    Journal of neurology

More on C9ORF72EXPANSION

Associations

1

Clinical severity

downin humans1

1 study

  1. Brainstem white matter ratio is associated with clinical severity in humans.

    “Clinical severity was negatively associated with the WM ratio.”

    Humansbrainstem

    Loss of brainstem white matter predicts onset and motor neuron symptoms in C9orf72 expansion carriers: a GENFI study

    Journal of neurology

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