Chromatin accessibility at progenitor and hair cell-specific gene loci

Biomarker

1 paper1 finding

Animals1

Upstream

FST

upin mouse cells1

1 study

FST increases chromatin accessibility at progenitor and hair cell-specific gene loci in mouse cells.
“FST augments TRIM71-induced increases in chromatin accessibility at progenitor and HC-specific gene loci, facilitating their transcriptional activation in SCs.”
Cellscoactivation with TRIM71cochlear supporting cell
A protein promoted hair cell regeneration in newborn mice
bioRxiv6 Oct 2026Preprint

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1 in 12 months

bioRxiv6 Oct

A protein promoted hair cell regeneration in newborn mice

Genetically modified newborn mice produced extra TRIM71, a protein that binds RNA, which promoted spontaneous regrowth of sound-detecting cells in the inner ear.Genetically modified newborn mice produced extra TRIM71, a protein that binds RNA, which promoted spontaneous regrowth of sound-detecting cells in the inner ear.

Preprint: experiments in miceEar

Paper

Chromatin accessibility at progenitor and hair cell-specific gene loci

Upstream

Latest

A protein promoted hair cell regeneration in newborn mice

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