Cholesterol excretion

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Liver x receptor agonist

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Liver x receptor agonist increases cholesterol excretion in mice (from 17 to 49 microg per day).
“Treatment with this LXR agonist increased cholesterol excretion out of brain from 17 to 49 microg per day”
Animalsin NPC1 micebrain
Liver X receptor activation enhances cholesterol loss from the brain, decreases neuroinflammation, and increases survival of the NPC1 mouse
The Journal of neuroscience : the official journal of the Society for Neuroscience26 Dec 2007

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The Journal of Neuroscience26 Dec

Liver X receptor activation enhances cholesterol loss from the brain, decreases neuroinflammation, and increases survival of the NPC1 mouse

Experiments in miceInterventions