Cdkn1a/p21

1 paper

Animals1

Latest

6 in 12 months

Iranian Journal of Pharmaceutical ResearchJul 26

Metformin Attenuates Angiotensin II-Induced Cardiac Inflammaging-Like Injury Through Coordinated Nrf2 Activation and NF-κB Suppression

Experiments in human cellsMetformin

Ageing Research ReviewsJul 5

Effects of nutritional interventions on biomarkers of cellular senescence in humans: A systematic review

Systematic review of randomized trialsInterventions

Stem Cells Translational MedicineJul 2

Inhibition of inflammation and senescence with azole compound C7 enables expansion of hematopoietic stem and progenitor cells

Experiments in animalsBlood and immune system

International Journal of Oral ScienceJun 4

OCT4-driven PER1 activation promotes odontogenic differentiation in senescent SCAP spheres

Experiments in animalsInterventions

bioRxivJan 16

p21 CIP1/WAF1 -mediated partial senescence supports steroidogenesis and therapy resistance in primary prostate cancer cultures

Preprint: experiments in human cellsCellular senescence

BiomaterialsNov 26

Target anesthesia and surgery induced senescent cell via composite microsphere hydrogels as nose-to-brain amplifiers of platelet factor 4 delivery for neurocognitive dysfunction repair

Experiments in miceNeurocognitive disorders

Frontiers in ImmunologyOct 24

Mechanistic insights and biomarker discovery in immune cell aging and age-associated diseases

ReviewImmune response

AutophagyOct 2

Aging-rewired metabolic cues promote autophagy and senescence via DRAM1

Experiments in miceAutophagy

AutophagySep 9

KDM4A-induced tumor senescence enhances the efficacy of immunotherapy by inhibiting AGT-PHB1 axis-mediated mitophagy in colorectal cancer

Cohort study in peopleMitophagy

Journal of Ginseng ResearchAug 22

Notoginsenoside R2 attenuates hepatic fibrosis via STAT3-dependent hepatic stellate cells senescence induction and inflammatory microenvironment suppression

Experiments in zebrafishInterventions