Cdkn2a/p16

1 paper

Animals1

Latest

6 in 12 months

Iranian Journal of Pharmaceutical ResearchJul 26

Metformin Attenuates Angiotensin II-Induced Cardiac Inflammaging-Like Injury Through Coordinated Nrf2 Activation and NF-κB Suppression

Experiments in human cellsMetformin

Ageing Research ReviewsJul 5

Effects of nutritional interventions on biomarkers of cellular senescence in humans: A systematic review

Systematic review of randomized trialsInterventions

International Journal of Oral ScienceJun 4

OCT4-driven PER1 activation promotes odontogenic differentiation in senescent SCAP spheres

Experiments in animalsInterventions

Clinical ScienceFeb 9

Intrarenal renin-angiotensin system inactivation ameliorates tubulopathy via attenuation of mitochondrial oxidative stress, dysfunction and senescence in diabetes

Experiments in miceRenin–angiotensin system

BiomaterialsNov 26

Target anesthesia and surgery induced senescent cell via composite microsphere hydrogels as nose-to-brain amplifiers of platelet factor 4 delivery for neurocognitive dysfunction repair

Experiments in miceNeurocognitive disorders

Inhalation ToxicologyNov 13

Genetic ablation of p16 leads to pulmonary remodeling, pro-senescence response, and immune modulation in mice exposed to low-dose, Sub-chronic, environmental tobacco smoke

Experiments in miceExtracellular matrix remodelling

bioRxivSep 12

Guided multi-agent AI invents highly accurate, uncertainty-aware transcriptomic aging clocks

Preprint: computational studyBiomarkers

AutophagySep 9

KDM4A-induced tumor senescence enhances the efficacy of immunotherapy by inhibiting AGT-PHB1 axis-mediated mitophagy in colorectal cancer

Cohort study in peopleMitophagy

Journal of Ginseng ResearchAug 22

Notoginsenoside R2 attenuates hepatic fibrosis via STAT3-dependent hepatic stellate cells senescence induction and inflammatory microenvironment suppression

Experiments in zebrafishInterventions

bioRxivMay 29

ICE: An imputation framework for detecting cellular senescence using weak single-cell signatures

Preprint: computational studyAI & data