Cancellous bone density

1. Age decreases cancellous bone density in humans.

   “HU values decreased with age (p < 0.001) and from cranial to caudal levels (p < 0.001), for both sexes (p < 0.001)”

   Humansspine

   Investigation of age- and sex-related changes in cancellous bone density in the human spine using CT · PloS one · 28 Sep 2026

1. Cancellous bone density is associated with bone volume fraction in humans (r = 0.51; 95% CI: 0.17-0.75).

   “HU values were correlated with BMD (r = 0.86; 95% CI: 0.72-0.94) and with BV/TV (r = 0.51; 95% CI: 0.17-0.75).”

   Humansspine

   Investigation of age- and sex-related changes in cancellous bone density in the human spine using CT · PloS one · 28 Sep 2026

Bone volume fraction →

1. Cancellous bone density is associated with bone mineral density in humans (r = 0.86; 95% CI: 0.72-0.94).

   “HU values were correlated with BMD (r = 0.86; 95% CI: 0.72-0.94) and with BV/TV (r = 0.51; 95% CI: 0.17-0.75).”

   Humansspinen = 71

   Investigation of age- and sex-related changes in cancellous bone density in the human spine using CT · PloS one · 28 Sep 2026

Bone mineral density →