Calcitonin gene-related peptide

1. ERCC1 has no effect on calcitonin gene-related peptide in mice (8.07 ± 1.15 vs 6.10 ± 0.57, P = 0.364).

   “No differences were observed in CGRP release between Ercc1Δ/-and wild type mice in the TNC (8.07 ± 1.15 versus 6.10 ± 0.57, P = 0.364)”

   Animalsin Ercc1Δ/- mice vs wild type controlstrigeminal nucleus caudalis

   Trigeminovascular calcitonin gene-related peptide release and peripheral vascular responses in a mouse model of accelerated aging: Implications for migraine

   The journal of headache and pain·Jul 3, 2026

2. ERCC1 decreases calcitonin gene-related peptide in mice (2.01 ± 0.24 vs 3.22 ± 0.48, P = 0.040).

   “CGRP release (expressed as ratio compared to baseline release) of the DM was significantly lower in Ercc1Δ/- (2.01 ± 0.24) versus wild type mice (3.22 ± 0.48) (P = 0.040).”

   Animalsin Ercc1Δ/- mice vs wild type controlsdura mater

   Trigeminovascular calcitonin gene-related peptide release and peripheral vascular responses in a mouse model of accelerated aging: Implications for migraine

   The journal of headache and pain·Jul 3, 2026

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