BrainPAD

Biomarker

2 papers3 findings

  • Human trial1
  • Humans1

Interventions

1

Meditation

downin humans1

1 study
  1. Meditation decreases BrainPAD in humans.

    “Compared to CUOA, OldExpMed exhibited significantly lower/more negative BrainPAD, linked to meditation hours, mental imagery, and prosocialness.”

    Humanslong-term practice (> 20 years)

    Impact of meditation on brain age derived from multimodal neuroimaging in experts and older adults from a randomized trial

    Scientific reports28 Oct 2025

More on Meditation

Effects

1

Cognitive function

no changein humans1

1 study
  1. BrainPAD has no effect on cognitive function in humans.

    “BrainPAD was not associated with any cognitive variable.”

    Humanscognitively-intactbrainn = 206

    Your brain doesn't look a day past 70! Cross-sectional associations with brain-predicted age in the cognitively-intact oldest-old

    GeroScience11 Dec 2025

Upstream

1

Female sex

downin humans1

1 study
  1. Female sex decreases BrainPAD in humans (B = -2.9, 95% CI = -4.6, -1.1, p = 0.002).

    “Women showed more-delayed brain aging than men (B = -2.9, 95% CI = -4.6, -1.1, p = 0.002).”

    Humanscognitively-intactbrainn = 206

    Your brain doesn't look a day past 70! Cross-sectional associations with brain-predicted age in the cognitively-intact oldest-old

    GeroScience11 Dec 2025

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