Brain structure

Biomarker

1 paper

  • Humans1

Funding

4 grants since 2023

National Institute on AgingUS$4.7mNational Institute of Neurological Disorders and StrokeUS$194.4k

Latest

Nov 2025: 2Dec 2025: 68Jan 2026: 7Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 1Jul 2026: 7Aug 2026: 16Sep 2026: 19Oct 2026: 7127 in 12 months
Brain Structure & Function

Post-menopausal women show larger brain regions in UK study

Brain scans from 4,098 women revealed greater gray matter volume and cortical thickness in specific regions among post-menopausal compared with pre-menopausal women.Brain scans from 4,098 women revealed greater gray matter volume and cortical thickness in specific regions among post-menopausal compared with pre-menopausal women.

Cross-sectional study of 4,098 peoplePopulations
Food & Function

Gut metabolites linked to preserved brain thickness in older adults

In a 104-person trial sub-study, rising levels of gut-produced urolithins tracked with preserved cortical thickness over two years in 55 older adults eating walnuts.In a 104-person trial sub-study, rising levels of gut-produced urolithins tracked with preserved cortical thickness over two years in 55 older adults eating walnuts.

Cohort study of 104 peopleInterventions
Environmental Pollution

Air pollution linked to faster brain tissue loss in adults

An observational study followed brain scans from 4,276 middle-aged and older adults, linking higher exposure to particle pollution with faster grey matter loss.An observational study followed brain scans from 4,276 middle-aged and older adults, linking higher exposure to particle pollution with faster grey matter loss.

Cohort study of 4,276 peoplePopulations
bioRxiv

Sex hormones link to cerebellar changes differently by sex

In 137 aging adults tracked across one year, changes in estradiol and testosterone showed opposing associations with cerebellar subregion volumes in men and women.In 137 aging adults tracked across one year, changes in estradiol and testosterone showed opposing associations with cerebellar subregion volumes in men and women.

Preprint: cohort study of 137 peopleMechanisms
NPJ Digital Medicine

Brain signatures of BMI detect systemic disease better than BMI

Across six human cohorts and a 2.3-year follow-up, neural networks identified brain structural patterns tied to cardiometabolic and pulmonary conditions.Across six human cohorts and a 2.3-year follow-up, neural networks identified brain structural patterns tied to cardiometabolic and pulmonary conditions.

Cohort study in peopleBiomarkers
Frontiers in Neurology

Osteocalcin links brain volume to cognition in osteoporosis

In people with osteoporosis, higher undercarboxylated osteocalcin correlated with greater medial prefrontal cortex volume, which predicted one-year cognitive decline with…In people with osteoporosis, higher undercarboxylated osteocalcin correlated with greater medial prefrontal cortex volume, which predicted one-year cognitive decline with an AUC of 0.84.

Cohort study in peopleOsteoporosis
Geriatrics & Gerontology International

Cortical surface areas link to fall-related fracture odds

Larger caudal anterior cingulate area linked to lower simple-fall fracture odds (OR 0.95), while larger insula area linked to higher odds (OR 1.05).Larger caudal anterior cingulate area linked to lower simple-fall fracture odds (OR 0.95), while larger insula area linked to higher odds (OR 1.05).

Mendelian randomisation in 51,000 peopleBones and joints