Biphasic plasma molecular signature

Age is associated with biphasic plasma molecular signature in mice (Sharp acceleration beyond 85% of lifespan).

“Aging showed a biphasic signature with sharp acceleration beyond 85% of lifespan, demarcating terminal decline.”

AnimalsTerminal declineplasman = 960

A multiomic lifespan signature in genetically diverse, diet-restricted mice

bioRxiv (Cold Spring Harbor Laboratory)·13 May 2026Preprint