3 papers5 findings
Cancer
upin humans1HR 1.16
Biological health score raises the risk of cancer in humans (HR 1.16, 95% CI 1.01-1.41).
“higher cancer incidence in men (1.16, 1.01-1.41)”
Humansmalesn = 9,782
Health score changes linked to disadvantage and later deaths
EClinicalMedicine29 Sep 2026
Atherosclerotic cardiovascular disease
upin humans1HR 1.33
Biological health score raises the risk of atherosclerotic cardiovascular disease in humans (HR 1.33, 95% CI 1.13-1.57).
“higher AS-CVD incidence in men (1.33, 1.13-1.57)”
Humansmalesn = 9,782
Health score changes linked to disadvantage and later deaths
EClinicalMedicine29 Sep 2026
Mortality
upin humans1HR 1.46
Biological health score raises the risk of mortality in humans (HR 1.46, 95% CI 1.25-1.71).
“higher all-cause mortality in both men (hazard ratio [HR] 1.46, 95% CI 1.25-1.71)”
Humansmalesn = 9,782
Health score changes linked to disadvantage and later deaths
EClinicalMedicine29 Sep 2026
Self-rated health
downin humans1
Biological health score is associated with self-rated health in humans (coefficient = -0.06).
“Biological Health Score was negatively associated with self-rated health (coefficient = -0.06)”
Humans
The journals of gerontology. Series A, Biological sciences and medical sciences30 Dec 2025
Physical function
downin humans1
Biological health score is associated with physical function in humans.
“Accelerated biological aging was found to be associated with worse functioning both cross-sectionally and longitudinally.”
Humans
The journals of gerontology. Series A, Biological sciences and medical sciences30 Dec 2025
Compared with no score change, a one-unit rise was linked to relative death rates of 1.46 in men and 1.26 in women.Compared with no score change, a one-unit rise was linked to relative death rates of 1.46 in men and 1.26 in women.