apoC3
2 papers study it27 more mention it
8 new papers in 30 daysSee all 29
- Humans2
Funding
1 grant since 2018National Heart, Lung, and Blood InstituteUS$2.1m
Latest
17 papers in 12 monthsAtherosclerosis
Drug target Mendelian randomization supports apolipoprotein C3-lowering for lipoprotein-lipid levels reductions and cardiovascular diseases prevention
Mendelian randomization in 35,378 peopleMechanisms
Neurobiology of Aging
Plasma apolipoproteins and physical and cognitive health in very old individuals
Cohort study of 1,067 peopleBiomarkers
Current Atherosclerosis Reports
Targeting Apolipoprotein C-III in Hypertriglyceridemia: Implications for Pancreatitis and Cardiovascular risk
ReviewAcute pancreatitis
ESC Congress 2026 Abstract
Apolipoprotein and inflammatory biomarker changes following marked triglyceride reduction with the GalNAc-conjugated APOC3 siRNA RBD5044
Randomized trial in peopleInterventions
ESC Congress 2026 Abstract
ION775, a long-acting siRNA targeting APOC3: single-dose, 12-month results in participants with moderate hypertriglyceridemia
Randomized trial in 40 peopleHypertriglyceridemia
ESC Congress 2026 Abstract
Mechanisms underlying ApoC3-mediated PM2.5-Induced atherosclerotic cardiovascular disease
Experiments in miceAPOC3
Current Hypertension Reviews
Cognitive Functions and Gene Polymorphism Associated with Cardiovascular Risk in Young Adults vs. Patients with Arterial Hypertension
Cross-sectional study of 152 peopleArterial hypertension
Nutrition Reviews
Comparative Effects of Low-Fat and High-Fat Diets on Non-HDL Cholesterol, Apolipoproteins, and Lipoprotein Ratios: A Meta-Analysis of Randomized Controlled Trials
Meta-analysis of randomized trialsInterventions
European Journal of Pharmacology
Effectiveness and Safety of Target-Specific RNA-Based Lipid-Lowering Therapies: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta-analysis of randomized trialsInterventions
Annual Review of Pharmacology and Toxicology
Small Interfering RNA in Cardiovascular Disease: A New Frontier in Precision Medicine
ReviewCardiovascular disease