Antimicrobial gene expression

Biomarker

1 paper1 finding

Model organisms1

Interventions

6-ppd quinone

downin worms1

1 study

6-ppd quinone decreases antimicrobial gene expression in worms.
“6-PPDQ at adult day-12 induced more severe immunosuppression reflected by decrease in expression of antimicrobial genes (lys-1, lys-7, spp-1, and dod-6) compared to that at adult day-8.”
Model organismslys-1, lys-7, spp-1, and dod-6 expression
6-PPD quinone at environmentally relevant concentrations induces immunosenescenece by causing immunosuppression during the aging process
Chemosphere12 Nov 2024

Latest

1 in 12 months

Communications Biology8 Oct

Disabling an enzyme shortened lifespan more in male flies

An experiment in Drosophila flies found changes in movement, sleep and brain structure in both sexes, with more severe movement deficits in males.An experiment in Drosophila flies found changes in movement, sleep and brain structure in both sexes, with more severe movement deficits in males.

Experiments in fliesMechanisms

Paper

Chemosphere14 Nov

6-PPD quinone at environmentally relevant concentrations induces immunosenescenece by causing immunosuppression during the aging process

Experiments in wormsMechanisms