The two-year combined outcome rate was 15.6% for sodium-glucose cotransporter 2 inhibitors versus 19.9% for renin-angiotensin system inhibitors, the comparison drug…The two-year combined outcome rate was 15.6% for sodium-glucose cotransporter 2 inhibitors versus 19.9% for renin-angiotensin system inhibitors, the comparison drug class.
Patients taking an ARNI had an adjusted hazard ratio of 0.6 for osteoporosis compared with those taking an ACE inhibitor.Patients taking an ARNI had an adjusted hazard ratio of 0.6 for osteoporosis compared with those taking an ACE inhibitor.
Incidence of all-cause dementia was 1.26 per 1000 person-years with RAS inhibitors versus 1.89 with calcium channel blockers (HR 0.68).Incidence of all-cause dementia was 1.26 per 1000 person-years with RAS inhibitors versus 1.89 with calcium channel blockers (HR 0.68).