Age-related changes in chromatin accessibility

1. Age-related changes in DNA methylation is associated with age-related changes in chromatin accessibility in humans.

   “Integration with ATAC-seq data revealed no clear relationship between age-related changes in DNA methylation and chromatin accessibility.”

   HumansNo clear relationship detectedblood

   Genome-wide multi-layered epigenomic profiling across human aging

   bioRxiv (Cold Spring Harbor Laboratory)·27 Jul 2026Preprint

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