There is 1 paper on activated ERK1/2 in aging research: none in people yet, 1 in animals.
1 paper studies it11 more mention it2 findings
- Animals1
Interventions
1Short-term fasting
upin rats1
1 study
Short-term fasting
upin rats1
Short-term fasting increases activated ERK1/2 in rats.
“The levels of activated ERK1/2 were increased after six-hour fasting.”
Animalshypothalamussix hours
Short-term fasting differentially regulates PI3K/AkT/mTOR and ERK signalling in the rat hypothalamus
Mechanisms of ageing and development
Associations
1Activated insulin receptor
upin rats1
1 study
Activated insulin receptor
upin rats1
Activated insulin receptor is associated with activated ERK1/2 in rats.
“activated ERK1/2 was co-expressed with activated insulin receptor in the nucleus arcuatus”
Animalsarcuate nucleus
Short-term fasting differentially regulates PI3K/AkT/mTOR and ERK signalling in the rat hypothalamus
Mechanisms of ageing and development
Latest
1 paper in 12 monthsMechanisms of Ageing and Development
Short-term fasting differentially regulates PI3K/AkT/mTOR and ERK signalling in the rat hypothalamus
Experiments in ratsPI3K–AKT signaling
Mechanisms of Ageing and Development
The TGF-β1-oxidative stress axis underlies accelerated senescence of endothelial cells exposed to serum from hypertensive patients
Experiments in human cellsOxidative stress and ROS signaling
Chemico-biological Interactions
Benzophenone-3 drives osteoarthritis pathogenesis by regulating chondrocyte senescence
Experiments in ratsCellular senescence
Advanced Science
Urolithin A Hijacks ERK1/2-ULK1 Cascade to Improve CD8⁺ T Cell Fitness for Antitumor Immunity
Experiments in animalsUrolithin A
Biomolecules & Biomedicine
Exogenous spermidine alleviates diabetic cardiomyopathy via suppressing reactive oxygen species, endoplasmic reticulum stress, and Pannexin-1-mediated ferroptosis
Experiments in miceSpermidine
Cellular and Molecular Gastroenterology and Hepatology
Insulin-Like Growth Factor1 Preserves Gastric Pacemaker Cells and Motor Function in Aging via ERK1/2 Activation
Experiments in miceInterventions
JCI Insight
Senescent hepatic stellate cells promote liver regeneration through IL-6 and ligands of CXCR2
Experiments in miceCellular senescence
Annals of Translational Medicine
Constitutive activation of ERK1/2 signaling protects against myocardial ischemia via inhibition of mitochondrial fragmentation in the aging heart
Experiments in animalsInterventions
Korean Circulation Journal
Angiotensin II Type 1 Receptor Blocker, Fimasartan, Reduces Vascular Smooth Muscle Cell Senescence by Inhibiting the CYR61 Signaling Pathway
Experiments in human cellsp38 MAPK signaling