Mechanisms of Ageing and Development
The TGF-β1-oxidative stress axis underlies accelerated senescence of endothelial cells exposed to serum from hypertensive patients
Experiments in human cellsOxidative stress and ROS signaling
Papers on activated ERK1/2
12 papers
Saturday, November 29
Thursday, October 2
Chemico-biological Interactions
Benzophenone-3 drives osteoarthritis pathogenesis by regulating chondrocyte senescence
Experiments in ratsCellular senescence
Wednesday, March 6
Advanced Science
Urolithin A Hijacks ERK1/2-ULK1 Cascade to Improve CD8⁺ T Cell Fitness for Antitumor Immunity
Experiments in animalsUrolithin A
Monday, September 4
Biomolecules & Biomedicine
Exogenous spermidine alleviates diabetic cardiomyopathy via suppressing reactive oxygen species, endoplasmic reticulum stress, and Pannexin-1-mediated ferroptosis
Experiments in miceSpermidine
Sunday, June 11
Cellular and Molecular Gastroenterology and Hepatology
Insulin-Like Growth Factor1 Preserves Gastric Pacemaker Cells and Motor Function in Aging via ERK1/2 Activation
Experiments in miceInterventions
Tuesday, November 15
Friday, June 17
JCI Insight
Senescent hepatic stellate cells promote liver regeneration through IL-6 and ligands of CXCR2
Experiments in miceIL-6 signaling
Thursday, April 15
Annals of Translational Medicine
Constitutive activation of ERK1/2 signaling protects against myocardial ischemia via inhibition of mitochondrial fragmentation in the aging heart
Experiments in animalsInterventions
Wednesday, September 23
Mechanisms of Ageing and Development
Short-term fasting differentially regulates PI3K/AkT/mTOR and ERK signalling in the rat hypothalamus
Experiments in ratsPI3K–AKT signaling
Saturday, May 11
Korean Circulation Journal
Angiotensin II Type 1 Receptor Blocker, Fimasartan, Reduces Vascular Smooth Muscle Cell Senescence by Inhibiting the CYR61 Signaling Pathway
Experiments in human cellsp38 MAPK signaling
Saturday, July 23
Experimental Cell Research
Dual roles of ERK1/2 in cellular senescence induced by excess thymidine in HeLa cells
Experiments in human cellsCellular senescence
Saturday, December 20
Tumour Biology
Fisetin suppresses ADAM9 expression and inhibits invasion of glioma cancer cells through increased phosphorylation of ERK1/2
Experiments in human cellsFisetin