Aβ-PET centiloid
2 papers3 findings
- Humans2
Upstream
2sTREM2
mediatesin humans1downin humans1
1 study
sTREM2
mediatesin humans1downin humans1
sTREM2 mediates Aβ-PET centiloid in humans (attenuation by 27%).
“attenuating the relationship between p ‐tau 231 and Aβ‐PET accumulation by 27%”
Humansmediates association between p-tau231 and Aβ-PET accumulationbrain
AAIC 2025 abstractDec 23, 2025
sTREM2 decreases Aβ-PET centiloid in humans (β -1.67 (95% CI -2.83 to -0.51), p < 0.01).
“Notably, higher sTREM2 was associated with reduced rates of Aβ accumulation (β [95% CI]: ‐1.67 [‐2.83 to ‐0.51], p <0.01)”
Humansbrain
AAIC 2025 abstractDec 23, 2025
P-TAU231
upin humans1
1 study
P-TAU231
upin humans1
P-TAU231 increases Aβ-PET centiloid in humans (β 0.98 (95% CI 0.26–1.69), p < 0.01).
“Higher CSF p ‐tau 231 levels were associated with faster Aβ‐PET accumulation (β [95% CI]: 0.98 [0.26–1.69], p <0.01).”
Humansbrain
AAIC 2025 abstractDec 23, 2025
Latest
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Plasma p-tau217 for detecting Aβ-PET positivity and tracking early amyloid accumulation in cognitively unimpaired ADNI participants
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AAIC 2025 Abstract
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