David W. Fardo
University of Kentucky2 papersORCID 0000-0002-7207-4696OpenAlex
Papers
medRxivHumansPreprint
Extreme polygenic risk scores track high Alzheimer's risk
In an analysis of 30,521 individuals, no controls were observed among 54 participants with extreme polygenic risk scores across European and African…In an analysis of 30,521 individuals, no controls were observed among 54 participants with extreme polygenic risk scores across European and African ancestries.
medRxivIn silicoPreprint
Alzheimer's polygenic risk scores vary widely across models
Across 1,752 models, correlations ranged from -0.49 to 1, with more than 95% of individuals placing in both the top and bottom risk deciles.Across 1,752 models, correlations ranged from -0.49 to 1, with more than 95% of individuals placing in both the top and bottom risk deciles.