James D. Brenton

University of Cambridge1 paperORCID 0000-0002-5738-6683OpenAlex

Papers

Nature GeneticsHumans

Germline HRD limits therapy-driven clonal hematopoiesis

Serial blood samples revealed carboplatin and PARP inhibitors expand DNA damage response clones, though germline homologous recombination deficiency…Serial blood samples revealed carboplatin and PARP inhibitors expand DNA damage response clones, though germline homologous recombination deficiency reduces this growth.