Art Schuermans
Broad Institute3 papersORCID 0000-0001-8146-9692OpenAlex
Papers
medRxivHumansPreprint
ASXL1 mutations in clonal hematopoiesis accelerate aortic valve calcification
Large human cohort data and cell experiments show that ASXL1-driven clonal hematopoiesis worsens aortic valve hemodynamics and promotes calcification…Large human cohort data and cell experiments show that ASXL1-driven clonal hematopoiesis worsens aortic valve hemodynamics and promotes calcification through inflammatory signaling.
JAMA CardiologyIn silico
Global heart failure cases reached 56 million in 2023
A Global Burden of Disease analysis across 204 countries estimated 56.0 million prevalent heart failure cases in 2023, with rates generally increasing…A Global Burden of Disease analysis across 204 countries estimated 56.0 million prevalent heart failure cases in 2023, with rates generally increasing with age.