No phaseCompleted
Exercise Training and Kidney Transplantation (EXTRA)
Exercise Training in Kidney Transplant Recipients (EXTRA Trial) Evaluating Physiological and Molecular Outcomes
- Sponsor
- Hugo de Luca Correa (Academic or other)
- Enrolment
- 345 enrolled
- Conditions
- Solid Organ Transplant Rejection; Chronic Kidney Failure; Quality of Life; Inflammation; Muscle Weakness
- Interventions
- Exercise training; Continue exercising; Discontinue exercising
- Ages
- adults
- Registry
- NCT06216015
From the registry
The goal of this clinical trial is to investigate the physiological and molecular effects of exercise training in transplant recipients. The main questions it aims to answer are: 1. Can exercise training improve physical fitness and muscle strength in transplant recipients? 2. Can exercise training modulate inflammatory profile, hormones, lipid profile, and exercise-induced molecules in transplant recipients? 3. Can exercise training improve blood pressure and endothelial health in transplant patients? Participants will be invited to an exercise training program 6-month after their transplant surgery. Body composition, physical assessment, and blood draw will be assessed at baseline and 24-weeks after exercise or control regimen. Researchers will compare exercise group vs. routine care group to see if exercise training impact the health-related outcomes of this population.
Primary outcomes
- Physical fitness - VO2peak
- Isometric muscle strength