No phaseCompleted
To Evaluate the Efficacy and Safety of NMN as an Anti-ageing Supplement in Middle Aged and Older (40-65 Years) Adults
A Multi Center Two Part Study to Evaluate the Efficacy and Safety of NMN as an Anti-ageing Supplement in Middle Aged and Older (40-65 Years) Adults
- Sponsor
- Abinopharm, Inc (Research network)
- Enrolment
- 90 enrolled
- Conditions
- Aging
- Interventions
- Nicotinamide Mononucleotide; Placebo
- Ages
- adults, older adults
- Registry
- NCT04823260
From the registry
It will be a two-part study. Part I will be six arms; randomized, double blind, parallel design, placebo-controlled dose ranging study. Part II will be open-label single dose study at the highest dose. A total of 90 Subjects (Part 1 \& Part 2) will be enrolled in the study. The Part 1 group subjects (80 Subjects) shall be randomly distributed between the six arms, i.e. 20 Subjects each in IP arms, and 7, 7 and 6 subjects in corresponding placebo arms. All Part 2 Group subjects (10 Subjects) will be assigned into the cluster where all receive the maximum NMN dose (900 mg)
Primary outcomes
- Blood cellular NAD+/ NADH
- Six walking endurance test
- SF-36 questionnaire
- PART II : Telomerase test results