No phaseActive, not recruiting
Implementation of Multifaceted Patient-Centered Treatment Strategies for Intensive Blood Pressure Control in Minimize Cognitive Decline (IMPACTS-MIND)
Effectiveness of Implementing an Intensive Blood Pressure Reduction Intervention on Cognitive Decline in Low-Income and Minority Hypertensive Patients
- Sponsor
- Tulane University (Academic or other)
- Enrolment
- 1,306 enrolled
- Conditions
- Hypertension; Cognitive Decline
- Interventions
- Stepped-care protocol adapted from the SPRINT intensive-treatment algorithm
- Ages
- adults, older adults
- Registry
- NCT04797403
From the registry
The study will test a multifaceted strategy for implementing an intensive blood pressure intervention protocol targeting systolic BP \<120 mmHg on cognitive decline in racial minority and low-income hypertensive patients in primary care. The proposed study will generate urgently needed data on effective, adoptable, and equitable intervention strategies to reduce blood pressure-related cognitive decline in low- income and minority populations. If proven effective, the implementation strategy for intensive blood pressure reduction could be adapted and scaled up in diverse primary care settings to prevent cognitive decline and clinical dementia.
Primary outcomes
- Net difference in mean change in cognitive decline