No phaseActive, not recruiting

Implementation of Multifaceted Patient-Centered Treatment Strategies for Intensive Blood Pressure Control in Minimize Cognitive Decline (IMPACTS-MIND)

Effectiveness of Implementing an Intensive Blood Pressure Reduction Intervention on Cognitive Decline in Low-Income and Minority Hypertensive Patients

Sponsor
Tulane University (Academic or other)
Enrolment
1,306 enrolled
Conditions
Hypertension; Cognitive Decline
Interventions
Stepped-care protocol adapted from the SPRINT intensive-treatment algorithm
Ages
adults, older adults
Registry
NCT04797403

From the registry

The study will test a multifaceted strategy for implementing an intensive blood pressure intervention protocol targeting systolic BP \<120 mmHg on cognitive decline in racial minority and low-income hypertensive patients in primary care. The proposed study will generate urgently needed data on effective, adoptable, and equitable intervention strategies to reduce blood pressure-related cognitive decline in low- income and minority populations. If proven effective, the implementation strategy for intensive blood pressure reduction could be adapted and scaled up in diverse primary care settings to prevent cognitive decline and clinical dementia.

Primary outcomes

  • Net difference in mean change in cognitive decline
Full record on ClinicalTrials.gov