Early phase 1Completed
Topical-RAPA Use in Inflammation Reversal and Re-setting the Epigenetic Clock
An Innovative Proof-of-concept Approach to Identify Age-modulating Drugs Capable of Reversing Inflammation and Re-setting the Epigenetic Clock (Topical-RAPA)
- Sponsor
- The University of Texas Health Science Center at San Antonio (Academic or other)
- Enrolment
- 22 enrolled
- Conditions
- Aging; Epigenetics; Inflammatory Mediators
- Interventions
- Rapamycin Topical Ointment; Placebo
- Ages
- older adults
- Registry
- NCT04608448
From the registry
Topical Rapamycin ointment will be applied to participant forearms to test whether epigenetic changes in the skin are elicited.
Primary outcomes
- Change in Epigenetic Markers