Lindsey N. Williams
TwinStrand Biosciences
Also published as: Lindsey Williams
3 papersORCID 0000-0003-3757-2582OpenAlex
- Mitochondrion
- Mitochondrial DNA maintenance
- Oxidative stress and ROS signaling
- Somatic reversion mutations
- Duplex sequencing
- Uterine lavage
- Ovarian cancer
- TP53
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Papers
Nature Ecology & Evolution
Mitochondrial haplotype and mito-nuclear matching drive somatic mutation and selection throughout ageing
Experiments in miceMitochondrion
bioRxiv
Mitochondrial haplotype and mito-nuclear matching drive somatic mutation and selection throughout aging
Preprint: experiments in miceMitochondrion
Cell Reports
Ultra-Sensitive TP53 Sequencing for Cancer Detection Reveals Progressive Clonal Selection in Normal Tissue over a Century of Human Lifespan
Cross-sectional study in peopleTP53
Works at
Director of assay development
Sources: reporter.nih.gov
Grants and prizes
R44, Early Detection of Ovarian Cancer Using Uterine Lavage and Duplex Sequencing, R44CA221426, 2018–2021, Sep 5, 2019
Sources: reporter.nih.gov
Earlier work
- The FASEB Journal2025
Sex and Age but Not Body Mass Index (BMI) Predict Serum Retinol Binding Protein 4 (RBP4) and Transthyretin (TTR) Concentrations
- Mutation Research/Genetic Toxicology and Environmental Mutagenesis2023
Adopting duplex sequencing technology for genetic toxicity testing: A proof-of-concept mutagenesis experiment with N-ethyl-N-nitrosourea (ENU)-exposed rats
- Environmental and Molecular Mutagenesis2021
Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing DNA damage with the CometChip and mutagenesis by Duplex Sequencing
- Cytotherapy2021
Ultra-sensitive duplex sequencing for tracking of allogeneic cell therapies
- Proceedings of the National Academy of Sciences2020
Direct quantification of in vivo mutagenesis and carcinogenesis using duplex sequencing