Somatic reversion mutations

mito-nuclear mismatch is associated with somatic reversion mutations in mice.

“identify an extensive enrichment in somatic reversion mutations that 're-align' mito-nuclear ancestry within an organism's lifespan.”

Animalsthree tissues

Mitochondrial haplotype and mito-nuclear matching drive somatic mutation and selection throughout ageing

Nature ecology & evolution·15 Feb 2024