AgingResearch.NewsJoin free

Duplex sequencing

Duplex sequencing has been studied in 1 paper since 2019: 1 observational study in people. The newest paper, Jul 2, 2019: “Ultra-Sensitive TP53 Sequencing for Cancer Detection Reveals Progressive Clonal Selection in Normal Tissue over a Century of Human Lifespan”.

Exposure

1 paper studies it1 findingUpdated

“We demonstrate 80% sensitivity for ovarian cancer detection using ultra-accurate Duplex Sequencing to identify TP53 mutations in uterine lavage.”
Ultra-Sensitive TP53 Sequencing for Cancer Detection Reveals Progressive Clonal Selection in Normal Tissue over a Century of Human LifespanCell reports2019doi:10.1016/j.celrep.2019.05.109

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: Mary Kay Foundation and 7 more
  • 1 of 1 finding with company ties
  • Humans1

What is Duplex sequencing linked with?

1

Studies link Duplex sequencing with 1 measure, most often ovarian cancer (1 study).

Ovarian cancer

upin humans1+80% sensitivity

1 study

  1. Duplex sequencing predicts ovarian cancer in humans (80% sensitivity).

    “We demonstrate 80% sensitivity for ovarian cancer detection using ultra-accurate Duplex Sequencing to identify TP53 mutations in uterine lavage.”

    HumansTP53 mutations identified in uterine lavageultra-accurateuterusfemales

    Ultra-Sensitive TP53 Sequencing for Cancer Detection Reveals Progressive Clonal Selection in Normal Tissue over a Century of Human Lifespan

    Cell reports

More on Ovarian cancer

Latest

Related