Jamil Nehme
University Medical Center Groningen
11 papersORCID 0000-0003-2771-2043OpenAlex
- Cellular senescence
- CDKN2A
- Cell cycle regulation
- Senescence-associated secretory phenotype (SASP)
- CDKN1A
- Senolytics
- Ganciclovir
- PARP1 inhibitor
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Papers
The EMBO Journal
SenFlag gene signature identifies senescent cells in mouse and human tissues through a conserved core transcriptional program
Computational studyBiomarkers
bioRxiv
Reproducible in vivo applications of the p16-3MR model in senescence research
Preprint: experiments in miceAI & data
Nature Aging
Converting cell death into senescence by PARP1 inhibition improves recovery from acute oxidative injury
Experiments in miceApoptosis
The FEBS Journal
High dietary protein and fat contents exacerbate hepatic senescence and SASP in mice
Experiments in miceInterventions
Works at
Universitair Medisch Centrum Groningen
Lead investigator
Sources: openalex.org
Grants and prizes
Nederlandse Organisatie voor Wetenschappelijk Onderzoek
Open Competitie ENW XS pakket 25-1, LIF6: A Genetic Key to Cancer Resistance and Healthy Aging?, OCENW.XS25.1.171, 2025, May 1, 2025
Sources: openalex.org
Earlier work
- The EMBO Journal2025
Pharmacological CDK4/6 inhibition promotes vulnerability to lysosomotropic agents in breast cancer
- Research SquarePreprint2024
Systemic Senolysis in Naturally Aged Mice Using a FAST-PLV Gene Therapy Approach